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Theses from 2023

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Optimizing Three-Dimensional Bioengineered Co-Cultures for the Study of Fibrotic Spinal Cord Injury, Sarah Aly

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Correlation of Intracellular Metabolites with Optical Metabolic Imaging in Polarized Macrophages as Indicators of Metabolic Reprogramming, Abby Claire Denison and Shelby Bess

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Exploring the Effects of Microarchitecture on Astrocyte Behavior and Vascular Remodeling in Spinal Cord Injury, Devin Gerber

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Automated Segmentation of Autofluorescence Lifetime Images Using a Convolutional Neural Network, Nicole Hooten

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Comprehensive long- and short- read sequencing approaches to screen the mutational landscape after therapeutic CRISPR-editing for Duchenne Muscular Dystrophy, Mary Jia, Made Harumi Padmaswari, Landon Burcham, Shilpi Agrawal, Alexis Ivy, Abbey Bryan, and Christopher E. Nelson

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Investigating the Impact of International Education on Cultural Understanding, Health Disparities and Collaboration through Project-Based Learning, Breanna Kilgore

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A Wheelchair-Bed Transfer Device for Patients with Limited Mobility, Malachie Nichols

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Investigating the Effect of Pancreatic Cancer Tumor-Derived Extracellular Vesicles on Schwann Cell Activation, Isabel Powers

Theses from 2022

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Hydrogel Drug Delivery Platform Integrity and Utilization Analysis, Joshua Carson Adams

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Characterizing the expression pattern and function of Tartan during Drosophila development, Alaina Baggett

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Pulse Rate Variability Analysis During Hemorrhage in an Experimental Porcine Model, Gabbie Bonvillain, Lauren Crimmins, Md Abul Hayat, Adria Abella Villafranca, Sam Stephens, Hanna K. Jensen, Joseph A. Sanford, Jingxian Wu, Kevin W. Sexton, and Morten Jensen

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The Effects of Microgravity on Human Endothelial Cells in Relation to Deep Vein Thrombosis, Allie Burgess

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Surface Laser Texturing of CoCrMo Alloys, Gabriel Dharwadker

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Restoring an ISO:5840-compliant Pulse Duplicator Device for Hydrodynamic Performance Characterization of Artificial Cardiac Valves, Denver Eagar

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Erythrocyte Deformability in Response to Glucose Using Liquid Crystals, Jayden Goff

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Disparities in response, motivations, and self-efficacy to Entrepreneurially Minded Learning within underrepresented students' groups, Kaitlin Hall

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Developing a Semester-Long Project in a Biomechanical Engineering Course to Instill the Entrepreneurial Mindset in the Next-Generation Biomedical Engineering Students, Loren Hedgecock

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Alternative Fixation of Venous Valves for Bioprosthetic Applications, Makenzie Kapales

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Investigating the Impact of Hypoxia on Reactive Oxygen Species Generation within Murine Breast Cancer Cells, Jared McPeake

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The influence of MMP14 on angiogenesis in chemotherapy-treated tumors, Abdussaboor Muhammad

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Assessing the Potential Effectiveness of Diffuse Reflectance Spectroscopy for Quantifying Neonatal Skin Properties using Tissue Phantoms, Jack Murphy

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Sequential Illumination in a Tomographic Microendoscopic Probe for Imaging Tumor Microvasculature, Zachariah Neumeier

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Clot Analogs for the Development of Improved Treatment Methods In Ischemic Stroke, Charles A. Rieth

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Modifications of a Machine to Produce Clinically-Sized Angioplasty Balloons for Bifurcations, Natalie Smith

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3D volumetric mapping of tissue properties via a catheter-scale microendoscope imaging system, Andrew Stark

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The Interaction of Angiotensin I and II on Calcified Aortic Valve Cells, Fah Sysavanh

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Determination of tissue-level changes in tumors that are indicative of metastasis using optical spectroscopy, Sanidhya D. Tripathi

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Virtual Reality as an Education Tool in Biomedical Engineering, Megan Wilkerson

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Localized Intra-Arterial Drug Delivery Device for Stroke Treatment, Benjamin Yip

Theses from 2021

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New Force Transducer for Mitral Valve Chordae Tendinea, Joseph Berryman

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Effects of IL-10 On Local Cell Populations and Functional Recovery Following VML Injury, Zain Blackwell

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Quantifying mucosal hemodynamics in a murine model of Ulcerative Colitis with diffuse reflectance spectroscopy, Elizabeth A. Bullard, Ariel I. Mundo, Shelby N. Bess, and Kathryn P. Miller

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Monitoring FGF1-Treated Skin Wounds with Label-Free Multiphoton Microscopy, Gianna Busch

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Involvement of the INO80 chromatin remodeling complex in cell division and genomic stability, Ethan Chen

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The Linear and Non-Linear Relationships between Peripheral Venous Pressure, Arterial Circulation, and Patient Factors, Lauren Crimmins

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Development of a SolidWorks Simulation Toolkit for a Sophomore Level Biomedical Engineering Course, Jordan Crosby

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Metabolic Profiling of Radiation Resistance in Head and Neck Squamous Cell Carcinoma, Natalie Curry

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Developing Aligned Nerve Scaffolds in a 3D Type-I Collagen Gel, Gabriel David

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Quantifying Blood Flow Patterns in the Pediatric Heart Using Blood Speckle Imaging, Harrison Dean

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Guide RNAs preparation for in-vitro CRISPR-Cas9 complex delivery targeting genes that affect wound healing., Prashant Khatiwada

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Static Force Analysis of a Porcine Mitral Valve to Determine Self-Supporting Capabilities of the Leaflets, Jacob Paris

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Evaluating Cellular Response of Different Valve Interstitial Cell (VIC) Phenotypes to Angiotensin I, Smit Patel

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Tissue Engineering and the Effect of Volumetric Muscle Loss on Muscle Performance, Alex Pemberton

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Quantification of Superoxide Production In Cells Treated with L-buthionine Sulfoximine, Rebekah Townsley

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Mapping the Domain of RNA Helicase DDX1 that Interacts with the NS1 of Influenza A Viruses, Elise Wyatt

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Expanding Image Datasets for Deep Learning by Evaluating Independence through Coefficient Correlation and Mean-Squared Error, Ayman Yousef

Theses from 2020

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Maximizing the Academic and Professional Success of First-Generation College Students in Biomedical Engineering, Mona Ahmed

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The Response of Astrocytes to Mechanical Stimuli, Courtney Bahan

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The Utilization of Autofluorescence to Study the Effects of L-buthionine-sulfoximine on Cellular Metabolism in Vitro, Madison Belew

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Differential Patterns of Theta Activation Underlying Various Cognitive Control Strategies, Jarrod Eisma

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Baseline Data Collection on the Overall Health of First-Year Engineering Students at the University of Arkansas, Braeley George

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Theoretical Applicability of CRISPR-Mediated Exon Skipping in Duchenne Muscular Dystrophy, Andrew Greek

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Comparative Genomics of Human Mesenchymal Stem Cells and Human Mesenchymal Stem Cells Derived Vascular Smooth Muscle Cells, Samia Ismail

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Redesign and Quantitative Assessment of an Accelerated Venous Valve Fatigue Apparatus, Megan Kueh

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Optical Metabolic Imaging as a Predictor of Patient Tumor Response to Therapy and Apoptosis, Andrew Larey

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Cell Line-Specific Differences in Guided Differentiation of Adipose-derived Mesenchymal Stem Cells Towards Smooth Muscle Cells, Sherly Makar

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Clinically relevant 3D characterization of simulated non-carious cervical dental lesions and the effects of toothbrush and toothpaste types on wear, James Needy

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Electrodialysis Device for In vivo power delivery, Jessica L. Orton

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Characterization of Oxone Mediated TEMPO-Oxidized Nano Cellulose Mixed-Matrix Membranes During Ultrafiltration and Hemodialysis, Kristyn Robling

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Analysis of Blood Purification Studies on Oxone Mediated TEMPO-Oxidized Nano Cellulose Mixed-Matrix Membranes, Tony Roller

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Stirred Suspension Bioreactor Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle Cells, Chris Slavin

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Development of a MATLAB GUI to Assist the Active Comprehension of Biomedical Transport Phenomena Using a Visual Aid, Pranav Suri

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Autofluorescence Spectral Unmixing for Quantitative Metabolic Imaging within Tissues, Lucy Woodbury

Theses from 2019

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Investigation of Acute Radiation-Induced Changes in Oxygenation in a Murine Breast Tumor Model, Alaa Abdelgawad

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Vector Flow Imaging in Pediatric Cardiology - Extracting and Validating Data, Mason Belue

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Effect of Polymer Composition of Injectable Hydrogels on Programmable Release of Methylene Blue, Mary Brandecker

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Development of a Model for Accelerated Fatigue Testing In Venous Valves, Olga Brazhkina

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How Infant Positioning Impacts Hip Motion and the Associated Implications for Babies with Hip Dysplasia, Lauren Buchele

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A Bioinstrumentation Active Learning Educational Module: The Design of a Working Temperature Sensor Using A NTC Thermistor, Baylor Bush

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Role of Angiotensin I and II on the Tissue Mechanics of the Aortic Heart Valve via Receptor Binding and Converting Enzymes, Josh Fahy

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Design of Microporous Membranes for the Development of Brain-on-Chip Devices, Andre Figueroa Milla

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Modeling and Validation of Tissue Optical Properties in the Photon Transport Regime, Katelyn Heath

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Phenotypic Characterization of Differentiation of Human Mesenchymal Stem Cells to Smooth Muscle Cells, Jackson Hedrick

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Comparing the Effects of Fibroblast Growth Factors on Growth Rate of Human Fibroblast Cell Lines, Tasha Repella

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Optical Spectrsocopy of Murine breast tumor to distinguish indolent from aggressive disease, Joel Rodriguez Troncoso

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Generation of a CCL2 knockout using CRISPR/CAS9 and lipid mediated transfection in CT-26 murine colon carcinoma cells, Emma Sullivan

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Designing an In Vitro Mitral Valve Mounting and Testing System for Micro CT Imaging, Marinna Tadros

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Investigating Virus Clearance via pH Inactivation During Biomanufacturing, Wenbo Xu

Theses from 2018

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Antibacterial Properties of a Cationic Imidazolium-Containing Poly(Ionic Liquid), Kaitlyn P. Brickey

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3D Printed Force Transducers for In-Vitro Mitral Valve Chordae Tendineae Force Measurements, Hayley Chandler

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Analysis of Biological Response to ECM Hydrogel Injection, Grady Dunlap

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Effects of GSK101 Exposure on Astrocyte Mechanical Properties, Collagen Production, and Viability, Ethan Echols

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In-Vitro Simulation of Acute Ischemic Stroke, Paolo Garcia

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Comparison of Varying Tissue Freezing Methods on Murine Colonic Tissue, James Hughes

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In Vitro Aortic Arch Flow Model For Vector Flow Imaging Testing, Jackson Mosley

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The Effect of Elastin Degradation on the Biomechanical Properties of Porcine Aortic Tissue, Caleb Nissen

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Pressure Acquisition System for In Vitro Mitral Valve Analysis, Laura Peck

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Role of Local Renin-Angiotensin System in Altering Valve Interstitial Cell Phenotype, Sophia Scalise

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Quantification of tumor-associated macrophages following immunomodulation therapy in a murine allograft model of colorectal carcinoma, Caroline Spainhour

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Development of an In Vitro Platform for the Exploration of Skeletal Muscle Cell Mechanobiology, Sydney Spradlin

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Extraction and Analysis of Vector Flow Imaging Data in a Pediatric Population, Bailey Stinnett

Theses from 2017

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Metabolic Response to Stress Differentiates Heterogeneous Cancer Cells with Varying Metastatic Potential, Kinan Alhallak

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Optimizing a Standard Fasting Time for 2-NBDG Uptake Studies in Murine Breast Cancers, Andrew C. Briley

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Optical Imaging of Metabolic Adaptability as a Biomarker for Metastatic Potential in Breast Cancer Cells, Mason G. Harper

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Detection of leukocytes stained with acridine orange using unique spectral features acquired from an image-based spectrometer, Courtney J. Hunter

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In vivo multi-parametric imaging of metastatic and non-metastatic breast cancer, Raisa B. Rasul

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Characterization of the Response of TRPV4 to Chemical Stimulation, Jacob V. Schluns

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Age's Effect on Regenerative Capabilities of Myocytes Through Satellite Cell Analysis, Karam S. Sra

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Role of TRPV4 in Astrocyte Extracellular Matrix Production, Abby Terlouw

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Effects of Uniaxial Cyclic Strain on Endothelial Progenitor Cells, Maria Alejandra Zeballos Castro